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Gut Microbiome Aging

Meaning

Gut Microbiome Aging refers to the characteristic, progressive, and often detrimental shifts in the composition, functional capacity, and overall diversity of the intestinal microbial community that accompany advancing chronological age. This process is typically marked by a significant reduction in beneficial bacterial species diversity and a corresponding increase in opportunistic or pro-inflammatory pathogens, resulting in a less resilient and metabolically less favorable gut ecosystem. This microbial drift is increasingly considered a critical, modifiable factor contributing directly to immunosenescence and age-related metabolic and hormonal decline.