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Gut-Hormone Connection

Meaning

The Gut-Hormone Connection describes the intricate, bidirectional communication network existing between the gastrointestinal tract, its resident microbiota, and the body’s entire endocrine system. This physiological axis involves the gut producing various crucial hormones, such as GLP-1, ghrelin, and serotonin, which directly influence systemic metabolism, satiety, and emotional mood. Furthermore, the diverse gut microbiome metabolizes and modulates circulating sex hormones, including estrogens and androgens, fundamentally impacting overall hormonal balance and systemic health. This connection is central to metabolic and longevity science.