Skip to main content

Gut-Brain Axis Signaling

Meaning

Gut-Brain Axis Signaling describes the complex, bidirectional communication network that links the enteric nervous system (ENS) within the gut to the central nervous system (CNS) via multiple conduits. This signaling profoundly influences mood regulation, cognitive function, and systemic endocrine control through afferent and efferent pathways. Disruptions in this axis are increasingly implicated in both systemic inflammatory states and metabolic disorders.