Skip to main content

Gut-Brain Axis Communication

Meaning

Gut-brain axis communication is the bidirectional biochemical signaling network that continuously links the central nervous system, including the brain, with the enteric nervous system of the gastrointestinal tract. This complex axis involves hormonal, neural, and immunological pathways, crucially mediated by the gut microbiota and their metabolites. The integrity of this communication is vital for regulating mood, stress response, appetite, and systemic inflammation.