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Gut-Brain Axis

Meaning

The Gut-Brain Axis (GBA) is the bidirectional biochemical signaling pathway that facilitates continuous communication between the central nervous system (the brain) and the enteric nervous system (the gut). This complex axis involves neural, hormonal, and immunological signaling, fundamentally linking emotional and cognitive centers of the brain with peripheral intestinal function. A balanced GBA is essential for optimal hormonal health, influencing mood, stress response, and metabolic regulation.