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Growth Hormone Signaling

Meaning

Growth Hormone Signaling describes the entire cascade of molecular events that occur within a target cell following the binding of Growth Hormone (GH) to its specific receptor, ultimately translating the hormonal message into a physiological response. This pathway is central to regulating body composition, bone density, and glucose and lipid metabolism throughout the lifespan. Disruptions in this intricate signaling network can lead to clinical conditions such as growth hormone deficiency or acromegaly.