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Growth Hormone Secretagogue Modulators

Meaning

Growth Hormone Secretagogue Modulators are a class of pharmaceutical or natural compounds that stimulate the body’s pituitary gland to increase the pulsatile release of endogenous Growth Hormone (GH). Unlike direct GH administration, these modulators work by mimicking the action of ghrelin or Growth Hormone Releasing Hormone (GHRH) at their respective receptors. Their clinical utility lies in their ability to restore a more youthful pattern of GH secretion, thereby improving body composition, bone density, and metabolic function with a potentially lower risk profile than exogenous hormone use. These compounds support the body’s intrinsic regulatory capacity.