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Growth Hormone Secretagogue Compliance

Meaning

Growth Hormone Secretagogue Compliance refers to the patient’s consistent and accurate adherence to the prescribed regimen of a Growth Hormone Secretagogue (GHS), which is a compound that stimulates the pituitary gland to release endogenous Growth Hormone (GH). This compliance is essential because the efficacy of GHS therapy relies heavily on maintaining a specific, often pulsatile, dosing schedule to maximize the physiological release of GH. Non-compliance, such as missed doses or incorrect timing, can significantly diminish the therapeutic stimulation of the somatotropic axis and subsequent IGF-1 production.