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Growth Hormone Pulse Restoration

Meaning

Growth Hormone Pulse Restoration is a clinical objective focused on re-establishing the youthful, pulsatile secretion pattern of Growth Hormone (GH) from the anterior pituitary gland, which naturally declines with age. This restoration is crucial because GH is secreted in distinct, high-amplitude pulses, predominantly during deep sleep, and this pattern is more physiologically active than a constant, low-level release. A successful restoration improves body composition, cellular regeneration, and metabolic profile. It is a key strategy for reversing somatopause.