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Growth Hormone Peptide Signaling

Meaning

Growth Hormone Peptide Signaling refers to the complex biological cascade initiated by Growth Hormone (GH) and its regulatory peptides, which culminates in systemic metabolic and anabolic effects. Growth Hormone is a polypeptide hormone released by the anterior pituitary gland, which primarily acts by stimulating the liver to produce Insulin-like Growth Factor 1 (IGF-1), a key mediator of its growth-promoting actions. This signaling pathway is critical for maintaining lean body mass, bone density, and glucose homeostasis throughout the lifespan. Understanding and modulating this signaling axis is a central focus in adult endocrinology and age management medicine.