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Growth Hormone Fluid Retention

Meaning

Growth Hormone Fluid Retention is a recognized, dose-dependent side effect of exogenous Growth Hormone (GH) administration, characterized by the accumulation of excess interstitial fluid. This phenomenon typically manifests as peripheral edema, often in the hands and feet, and can be accompanied by symptoms like carpal tunnel syndrome due to tissue swelling. It is a temporary physiological consequence that reflects the hormone’s influence on renal and electrolyte balance, particularly during the initial phases of therapy. This effect usually subsides as the body adapts to the new hormonal milieu.