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Growth Hormone Deficiency

Meaning

Growth Hormone Deficiency (GHD) is a clinical syndrome resulting from the inadequate secretion of growth hormone (GH) by the pituitary gland, leading to significant metabolic and physiological impairments. In adults, GHD is typically acquired, manifesting as a constellation of symptoms including adverse body composition changes, reduced bone mineral density, and impaired quality of life. The diagnosis requires specialized dynamic testing to confirm the failure of the pituitary to release sufficient GH in response to a stimulus.