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Growth Factor Signaling Fidelity

Meaning

Growth Factor Signaling Fidelity refers to the accuracy, consistency, and efficiency with which cells receive, process, and execute the instructions delivered by peptide growth factors, such as Insulin-like Growth Factor 1 (IGF-1) or Fibroblast Growth Factors (FGFs). High fidelity ensures that the intended biological message—often relating to cell proliferation, differentiation, or tissue repair—is transmitted without error or degradation. Loss of fidelity can lead to impaired tissue regeneration and contribute to aging or disease states. This is crucial for tissue maintenance.