Skip to main content

Growth Factor Receptor Agonism

Meaning

Growth Factor Receptor Agonism is a specific biochemical action where an exogenous or endogenous compound binds to and activates a cell-surface receptor designed for a growth factor, thereby initiating an intracellular signaling cascade that promotes cell proliferation, differentiation, or survival. This action is crucial in clinical settings for stimulating tissue repair, accelerating wound healing, and supporting the maintenance of lean body mass. Careful selection of the agonist is required to ensure targeted activation of beneficial pathways, such as those mediated by Insulin-like Growth Factor 1 (IGF-1) or various fibroblast growth factors.