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GrimAge Biomarker

Meaning

GrimAge is a sophisticated, second-generation epigenetic clock that estimates an individual’s biological age and predicts time-to-mortality with high accuracy, surpassing earlier chronological age proxies. This biomarker utilizes DNA methylation data from specific CpG sites to create a composite score that strongly correlates with morbidity and healthspan. Clinically, it serves as a powerful, quantitative tool for assessing the cumulative impact of lifestyle and environmental exposures on biological health.