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GPR41

Meaning

GPR41, or G Protein-coupled Receptor 41, is a crucial cell surface receptor primarily recognized for its role as a sensor for short-chain fatty acids (SCFAs), which are metabolites produced by the gut microbiota. This receptor is integral to the gut-endocrine axis, translating microbial activity into host physiological responses, including energy expenditure, appetite regulation, and intestinal motility. Its function is a key nexus point between microbiome health and systemic metabolic and hormonal balance. GPR41 is therefore a vital component in the emerging field of personalized wellness.