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Gonadotropin Releasing Hormone Dynamics

Meaning

Gonadotropin Releasing Hormone Dynamics refers to the critical pattern, frequency, and amplitude of the pulsatile secretion of GnRH from the hypothalamus, which is the master regulator of the entire reproductive axis. This dynamic, non-continuous release is the key determinant for the downstream secretion ratio of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) from the pituitary gland. Any alteration in these dynamics, whether too fast or too slow, can lead to profound reproductive and hormonal dysfunctions in both males and females.