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Gonadorelin Pulsatile Dosing

Meaning

Gonadorelin pulsatile dosing refers to the therapeutic administration of synthetic Gonadorelin, also known as Gonadotropin-Releasing Hormone (GnRH), in a rhythmic, intermittent pattern. This method precisely mimics the natural, intermittent secretion of GnRH from the hypothalamus, which is essential for proper physiological stimulation of the pituitary gland. It ensures that the endocrine system receives the necessary signals in a way that avoids receptor desensitization.