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Gonadorelin Protocol Rationale

Meaning

The scientific justification and clinical logic underpinning the use of Gonadorelin (or its synthetic analogue, Gonadotropin-Releasing Hormone – GnRH) in a specific therapeutic regimen, particularly to modulate the Hypothalamic-Pituitary-Gonadal (HPG) axis. This rationale typically centers on stimulating the endogenous production of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in a physiological, pulsatile manner to restore gonadal function. The primary goal is to maintain or re-establish fertility and endogenous hormone production while avoiding suppression.