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Gonadal Hormones Brain Function

Meaning

Gonadal Hormones Brain Function refers to the extensive and multifaceted impact of sex steroid hormones—primarily estrogens, progesterone, and testosterone—produced by the gonads (testes and ovaries) on the structure, neurochemistry, and functional output of the central nervous system. These hormones act as neurosteroids, modulating mood, cognition, memory, stress resilience, and neuroprotection across the lifespan in both males and females. The balance and availability of these hormones are critical determinants of cognitive health and emotional stability. Understanding this connection is essential for addressing age-related cognitive decline and mood disorders.