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Gonadal Hormone Output

Meaning

Gonadal Hormone Output refers to the quantitative and qualitative secretion of sex steroid hormones, primarily testosterone, estrogen, and progesterone, produced by the testes in males and the ovaries in females, under the regulatory control of the hypothalamic-pituitary-gonadal (HPG) axis. This output is critical for reproductive function, but also profoundly influences bone density, muscle mass, cognitive function, and cardiovascular health across the lifespan. Clinically, assessing this output involves measuring the circulating levels of these hormones to evaluate overall endocrine function and its impact on health and longevity. A robust output is a hallmark of youthful physiological function.