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Gonadal Hormone Kinetics

Meaning

Gonadal Hormone Kinetics describes the time-dependent processes governing the absorption, distribution, metabolism, and excretion (ADME) of sex steroids produced by the testes or ovaries. This analysis tracks how hormones like testosterone, estrogen, and progesterone move through the body following synthesis or administration. Understanding these kinetics is vital for determining appropriate dosing schedules and predicting steady-state tissue exposure. Deviations in kinetic profiles can lead to suboptimal therapeutic windows or hormonal fluctuations.