Gonadal Function Assessment is the systematic clinical evaluation of the primary reproductive glands—the testes in males and the ovaries in females—to determine their capacity for gamete production and sex hormone synthesis. This assessment moves beyond simple hormone levels to investigate the underlying physiological competence of these endocrine organs. We evaluate markers of steroidogenesis, follicular reserve, or spermatogenesis efficiency. A thorough assessment guides interventions aimed at reproductive and vitality support.
Origin
The term originates from ‘gonad,’ referring to the primary reproductive glands, ‘function,’ denoting their operational capability, and ‘assessment,’ the process of evaluation. Its importance is rooted in the foundational role gonads play in sexual development, secondary characteristics, and systemic hormonal milieu maintenance. This evaluation is central to reproductive endocrinology.
Mechanism
Assessment typically involves measuring baseline and stimulated levels of key hormones like testosterone, estradiol, FSH, and LH, alongside specific functional markers such as Inhibin B or Anti-Müllerian Hormone (AMH). In males, semen analysis provides direct functional data regarding spermatogenesis. The mechanism relies on understanding the HPG axis drive (FSH/LH) relative to the end-organ output (sex steroids), revealing potential primary gonadal failure or secondary axis suppression.
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