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Gonadal Axis Tuning

Meaning

The precise, clinical adjustment of the Hypothalamic-Pituitary-Gonadal (HPG) axis, which is the master regulatory system for sex hormone production in both males and females. Tuning involves strategically modulating the pulsatile release of Gonadotropin-Releasing Hormone (GnRH), Luteinizing Hormone (LH), and Follicle-Stimulating Hormone (FSH) to optimize the endogenous output of testosterone, estrogen, and progesterone from the gonads. The goal is to achieve a youthful, balanced hormonal milieu, improving fertility, libido, muscle mass, and bone density. This is a sophisticated intervention requiring deep endocrinological understanding.