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Gonadal Axis Function Testing

Meaning

Gonadal Axis Function Testing is a specialized set of diagnostic procedures designed to evaluate the integrity and output of the Hypothalamic-Pituitary-Gonadal (HPG) axis, the central regulatory system for reproductive and sexual hormones. This testing goes beyond measuring single hormone levels by including pituitary regulators like Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), along with the primary gonadal steroids, such as testosterone and estradiol. A thorough assessment is necessary to differentiate between primary gonadal dysfunction and secondary regulatory issues originating in the hypothalamus or pituitary.