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Gonadal Axis Function Optimization

Meaning

Gonadal Axis Function Optimization refers to the clinical strategy aimed at achieving the highest possible endogenous output and balanced regulation of sex hormones, including testosterone, estrogen, and progesterone, through the Hypothalamic-Pituitary-Gonadal (HPG) axis. This process seeks to restore the HPG axis to its youthful, efficient state of signaling and feedback sensitivity. The objective extends beyond simple hormone replacement, focusing on enhancing the body’s intrinsic capacity for hormonal production and rhythmic secretion.