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Goldilocks Zone Titration

Meaning

Goldilocks Zone Titration is a clinical methodology that involves the precise, iterative adjustment of a therapeutic dose, typically a hormone or supplement, to achieve an optimal, narrow range of physiological effect, avoiding both deficiency and excess. This approach recognizes that the ideal biological state, the “Goldilocks Zone,” is highly individualized and exists at a specific, balanced point rather than merely within a broad laboratory reference range. It prioritizes functional outcome and subjective well-being over mere numerical normalization.