Skip to main content

Glymphatic System

Meaning

The Glymphatic System is a recently characterized macroscopic waste clearance pathway specific to the central nervous system, primarily operating during sleep. This system facilitates the rapid exchange between cerebrospinal fluid (CSF) and interstitial fluid (ISF), effectively flushing metabolic waste products, including amyloid-beta and tau proteins, from the brain parenchyma. Its proper function is increasingly recognized as vital for cognitive health and neuro-longevity.