What is the Origin of Glycine Sleep Aid?

The concept stems from foundational neurochemistry research identifying glycine's role in the brain and spinal cord, combined with clinical studies observing its thermoregulatory and subjective sleep-enhancing effects in humans. Its use as a sleep aid leverages its natural physiological function rather than introducing a foreign compound.

What is the Mechanism of Glycine Sleep Aid?

As a non-essential amino acid, glycine functions primarily by binding to N-methyl-D-aspartate (NMDA) receptors and inhibitory glycine receptors in the brainstem and spinal cord, increasing chloride ion influx and hyperpolarizing the postsynaptic membrane. This inhibitory action calms neural activity. Furthermore, ingestion of glycine has been shown to increase peripheral blood flow, which facilitates the necessary drop in core body temperature for sleep initiation.

Glycine Sleep Aid

Meaning

Glycine Sleep Aid refers to the clinical use of the amino acid glycine as a supplemental agent to promote improved sleep quality and efficiency. Glycine acts as an inhibitory neurotransmitter in the central nervous system, helping to reduce core body temperature and facilitate the onset and maintenance of restorative sleep. It is utilized to address mild sleep disturbances without the sedative effects of traditional hypnotics.