The precision and stability with which an individual maintains blood glucose levels within a tight, healthy operational range, reflecting robust insulin sensitivity and pancreatic beta-cell function. High fidelity implies minimal excursions above or below the set point, even following carbohydrate challenges. This metric is intrinsically linked to long-term metabolic and cardiovascular health.
Origin
This term originates from metabolic physiology and diabetes research, where “fidelity” is used to denote the accuracy of a control system. Its application in wellness science emphasizes moving beyond merely avoiding overt diabetes to achieving superior metabolic regulation.
Mechanism
Fidelity is maintained by the coordinated action of insulin and counter-regulatory hormones like glucagon, alongside effective tissue responsiveness to insulin signaling. Factors such as visceral adiposity or chronic inflammation can degrade this fidelity by inducing peripheral insulin resistance. Optimizing muscle and liver glucose uptake pathways is central to sustaining high control fidelity.
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