What is the Context of Glycation End Products?

Occur in the body, accelerated by hyperglycemia, affecting metabolic health.

What is the Significance of Glycation End Products?

Linked to diabetic complications, aging, and cardiovascular disease.

Form via Maillard reaction, causing cross-linking and inflammation via RAGE.

Monitoring informs dietary and glycemic control strategies.

Measured in serum/urine or via skin autofluorescence.

Accumulation causes vascular stiffening and exacerbates chronic conditions.

Glycation End Products

Molecules formed by non-enzymatic sugar reactions with proteins/lipids.

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HRTioSeptember 27, 2025