Skip to main content

Glutamate Signaling

Meaning

Glutamate Signaling refers to the intricate process of chemical communication mediated by L-glutamate, the most abundant excitatory neurotransmitter in the mammalian central and peripheral nervous systems. This signaling pathway is crucial for nearly all aspects of brain function, including learning, memory, and neuronal development. In the context of hormonal health, it plays a key modulatory role within the neuroendocrine axis, affecting the release of hypophysiotrophic and pituitary hormones. Dysregulation of this system can be implicated in various neurological and psychiatric disorders.