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Glucose Transporter Type 4

Meaning

Glucose Transporter Type 4 (GLUT4) is an insulin-regulated protein responsible for facilitating the passive diffusion of glucose across the cell membrane into insulin-sensitive tissues, most notably skeletal muscle and adipose tissue. It is a critical, rate-limiting component of the body’s glucose disposal system, ensuring that blood sugar is efficiently moved out of the circulation and into cells for immediate energy use or storage. Proper functioning and trafficking of GLUT4 are essential for maintaining glucose homeostasis and preventing postprandial hyperglycemia.