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Glucose Hypometabolism Bypassing

Meaning

Glucose Hypometabolism Bypassing is a therapeutic strategy aimed at circumventing the reduced utilization of glucose by specific brain regions, a common feature in neurodegenerative and metabolic disorders. This approach involves introducing or enhancing the brain’s access to alternative, non-glucose energy substrates, most notably ketone bodies, to maintain adequate ATP production and neuronal function. It offers a metabolic rescue pathway when glucose uptake or processing is impaired. The goal is to restore neuroenergetic balance and support cognitive vitality.