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Glucoregulatory Mechanisms

Meaning

Glucoregulatory Mechanisms comprise the complex, tightly coordinated hormonal and neural feedback loops responsible for maintaining blood glucose concentrations within a narrow, physiological range. This system is primarily governed by the pancreatic hormones insulin and glucagon, which act antagonistically to manage glucose uptake, storage, and release by the liver, muscle, and adipose tissues. The proper function of these mechanisms is essential for preventing both hyperglycemia and hypoglycemia, thereby protecting vital organs, including the brain, from metabolic stress. Optimal glucoregulation is a fundamental marker of metabolic health and insulin sensitivity.