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Glucagonostatic Effect

Meaning

The Glucagonostatic Effect describes the physiological action of an agent, typically a hormone or pharmaceutical, that inhibits the secretion of glucagon from the pancreatic alpha cells. Glucagon is a catabolic hormone that raises blood glucose levels by promoting hepatic gluconeogenesis and glycogenolysis. By suppressing glucagon release, this effect contributes significantly to improved glucose homeostasis, particularly in states of insulin resistance or type 2 diabetes, helping to prevent inappropriate glucose output from the liver.