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Glucagon-Like Peptide Agonism

Meaning

Glucagon-Like Peptide Agonism is a pharmacological action achieved by administering synthetic compounds that functionally mimic the effects of the endogenous incretin hormone Glucagon-Like Peptide-1 (GLP-1), primarily targeting the GLP-1 receptor. These agents are clinically utilized to enhance glucose-dependent insulin secretion, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety, making them cornerstones in the management of type 2 diabetes and chronic weight management. The agonism provides a powerful, multi-faceted metabolic regulation signal.