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GLP-1 Agonists

Meaning

GLP-1 Agonists are a class of pharmaceutical compounds that mimic the action of Glucagon-Like Peptide-1, an incretin hormone naturally secreted by the L-cells of the small intestine in response to nutrient ingestion. These agents activate the GLP-1 receptor, leading to a cascade of beneficial metabolic effects, including glucose-dependent insulin secretion, slowed gastric emptying, and a significant reduction in appetite and food intake. They are clinically utilized for the management of type 2 diabetes and, increasingly, for weight management due to their profound impact on metabolic hormones.