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Glomerular Filtration

Meaning

Glomerular filtration is the initial and critical step in the formation of urine, occurring in the renal corpuscle of the kidney, where blood plasma is filtered across the glomerular capillary wall. This essential physiological process separates water and small solutes, including metabolic waste products and unbound hormones, from larger molecules like blood cells and plasma proteins. Maintaining a healthy Glomerular Filtration Rate (GFR) is a vital clinical indicator of renal function and overall metabolic clearance capacity.