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GIP Receptor Agonists

Meaning

GIP Receptor Agonists are a class of pharmacological agents designed to selectively bind to and activate the Glucose-dependent Insulinotropic Polypeptide (GIP) receptor. GIP is an incretin hormone released from the gut in response to nutrient ingestion, which enhances glucose-dependent insulin secretion from pancreatic beta cells. These agonists are clinically developed for the treatment of Type 2 Diabetes Mellitus and obesity, often utilized in combination with GLP-1 receptor agonists to achieve superior glycemic control and weight reduction. They leverage the body’s natural enteroendocrine system to improve metabolic health.