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GIP/GLP-1 Dual Agonists

Meaning

GIP/GLP-1 Dual Agonists represent a novel class of pharmacologic agents designed to simultaneously activate the receptors for two distinct incretin hormones: Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1). These agents mimic the action of the body’s natural gut hormones, providing a synergistic effect on glucose homeostasis, appetite regulation, and overall metabolic function. By engaging both receptor pathways, these compounds achieve superior efficacy in lowering blood glucose and promoting clinically significant weight loss compared to single-agonist therapies, offering a powerful tool in the management of Type 2 diabetes and obesity.