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GHSR-1a Activation

Meaning

GHSR-1a Activation refers to the specific stimulation of the Growth Hormone Secretagogue Receptor type 1a, a G protein-coupled receptor primarily located in the pituitary gland and hypothalamus, which is the endogenous receptor for the hormone ghrelin. Activating this receptor is a potent physiological mechanism for stimulating the pulsatile release of Growth Hormone (GH) from the somatotroph cells of the anterior pituitary. Clinical strategies often target this receptor to safely and naturally enhance endogenous GH secretion, which is a critical component of tissue repair, metabolic regulation, and maintaining youthful body composition.