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GHS R1a Receptor Binding

Meaning

GHS R1a Receptor Binding refers to the specific molecular interaction where a ghrelin secretagogue (GHS) or the endogenous hormone ghrelin attaches to the Growth Hormone Secretagogue Receptor type 1a, a G protein-coupled receptor. This binding event is the critical first step in activating the receptor, which subsequently triggers a cascade of intracellular signaling pathways. In the context of hormonal health, this action is paramount for stimulating the pulsatile release of growth hormone from the pituitary gland.