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GHRH Receptor Targeting

Meaning

GHRH Receptor Targeting is a specific pharmacological strategy focused on the selective activation of the Growth Hormone-Releasing Hormone (GHRH) receptors, which are situated on the somatotroph cells within the anterior pituitary gland. The therapeutic objective of this targeting is to stimulate the physiological, pulsatile release of endogenous growth hormone (GH) and its subsequent mediator, Insulin-like Growth Factor 1 (IGF-1). This sophisticated approach is utilized in clinical endocrinology to address the age-related decline in the somatotropic axis and its associated negative impacts on body composition and metabolic function.