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Ghrelin Modulation

Meaning

Ghrelin Modulation refers to therapeutic or lifestyle strategies aimed at regulating the synthesis, secretion, or receptor activity of ghrelin, a peptide hormone primarily produced by the stomach that functions as a potent appetite stimulant. This modulation is clinically relevant for managing energy balance, body weight, and metabolic health, as ghrelin is a key component of the gut-brain axis regulating hunger signals. Interventions seek to normalize the often dysregulated ghrelin profile seen in conditions like obesity or cachexia.