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Ghrelin Analogs

Meaning

Ghrelin analogs are synthetic compounds or pharmaceutical agents designed to mimic the biological actions of the endogenous hormone ghrelin, often referred to as the “hunger hormone,” which is primarily secreted by the stomach. These analogs typically target the growth hormone secretagogue receptor (GHSR-1a) in the hypothalamus and pituitary gland, promoting appetite stimulation and the release of growth hormone. In clinical settings, ghrelin analogs are investigated for their potential therapeutic utility in managing conditions characterized by cachexia, unintentional weight loss, or age-related growth hormone deficiency, offering a targeted approach to metabolic and anabolic support.