What is the Origin of GHK-Cu Peptide Science?

The peptide GHK was originally discovered in human plasma by Dr. Loren Pickart in 1973, with its concentration found to naturally decline with age. Its integration with copper, an essential cofactor for numerous enzymatic reactions, established its biological potency. GHK-Cu Peptide Science has since become a focus in dermatology, regenerative medicine, and longevity research due to its wide-ranging effects on cellular health and extracellular matrix renewal.

What is the Mechanism of GHK-Cu Peptide Science?

GHK-Cu functions by forming a stable complex that delivers copper into cells, where it acts as a transcription factor regulator, notably upregulating genes involved in tissue repair, collagen production, and antioxidant defense. It promotes the synthesis of collagen, elastin, and glycosaminoglycans, which are vital for skin firmness and elasticity. Furthermore, it exhibits a powerful anti-inflammatory effect by suppressing the activity of pro-inflammatory cytokines, thereby creating an optimal microenvironment for systemic regeneration and healing.

GHK-Cu Peptide Science ∞ Area

GHK-Cu Peptide Science

Meaning

The study and clinical application of the naturally occurring copper-binding tripeptide Glycyl-L-Histidyl-L-Lysine (GHK) complexed with copper (Cu), known as GHK-Cu. This small signaling peptide is recognized for its potent regenerative, anti-inflammatory, and antioxidant properties across various tissues. The science explores its role as a key modulator of gene expression related to tissue remodeling and wound healing.