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GH Pulse Restoration

Meaning

GH Pulse Restoration is a therapeutic objective focused on re-establishing the natural, pulsatile secretion pattern of Growth Hormone (GH) from the pituitary gland, which typically declines with age, a condition known as somatopause. The goal is to mimic the healthy, intermittent release of GH, particularly the large nocturnal pulse, to maximize its anabolic and lipolytic effects while minimizing potential side effects associated with continuous high levels. Restoring this pulse pattern is critical for maintaining lean body mass, bone density, and optimal metabolic function.