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GH-Independent

Meaning

GH-Independent describes a biological effect or physiological process that occurs without the direct or necessary action of Growth Hormone (GH), meaning the pathway is not reliant on GH stimulation. In the context of hormonal regulation, this distinction is important for understanding compensatory mechanisms or alternative signaling cascades that influence growth and metabolism. A process that is GH-independent is often regulated by other endocrine or paracrine factors, providing redundancy in physiological control. This indicates a separate regulatory axis.