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GH IGF-1 Axis Modulation

Meaning

GH IGF-1 Axis Modulation describes the clinical strategy of precisely regulating the somatotropic axis, which involves Growth Hormone (GH) secreted by the pituitary gland and its primary effector, Insulin-like Growth Factor 1 (IGF-1), produced mainly by the liver. This axis is fundamental to anabolic processes, including lean body mass maintenance, bone density, and metabolic homeostasis throughout the lifespan. Modulation aims to maintain levels that support optimal tissue repair and function while mitigating potential risks.